Disease data
Infection with Ranavirus
OIE listed diseases
Amphibians
Viral disease;
Ranavirus;
Ranavirus
Summary from the online OIE Diagnostic Manual
The most common presentation is an explosive mortality event with death due to peracute systemic haemorrhagic disease. In these cases, usually there are no external lesions. Skin vesicles have been reported with ATV infection in tiger salamanders( Ambystoma tigrinum ). A chronic ranavirus disease, characterised by skin ulceration and necrosis of the distal limbs, has been reported from the United Kingdom.In haematoxylin and eosin stained sections of skin, epithelial hyperplasia with disruption of the normal stratified architecture of the epidermis and often with necrosis of the deeper epithelial layers has been reported. Multiple foci of necrosis can be found in tissues, but these are rare in cases of the skin ulcerative form of disease. These necrotic foci are most obvious in the renal and splenic haematopoietic tissue and in the liver. Intracytoplasmic virus inclusions have been reported in a variety of tissues, most obviously in hepatocytes.
Infection has been demonstrated in all major tissues except for striated (skeletal) muscle, smooth muscle and cardiac muscle. However, virus can be isolated from skeletal muscle, probably from blood in tissues.
Countries affected
Country | Year | Status | View Records |
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Species affected
Species | Disease occurence | Abstract |
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Countries affected
Country | Year | Status | View Records |
---|---|---|---|
Albania | 2012 | Pathogen detected, no clinical disease. | View Records |
Americas | 2007 | Disease exists; distribution and occurrence unknown | View Records |
Argentina | 2006 | First detection in this host | View Records |
Australia | 2020 | Reported present or known to be present | View Records |
Belgium | 2012 | Reported present or known to be present | View Records |
Brazil | 2020 | Reported present or known to be present | View Records |
Canada | 2022 | Reported present or known to be present | View Records |
Chile | 2023 | See Publication | View Records |
China (Peoples Rep. of) | 2020 | Reported present or known to be present | View Records |
Colombia | 2023 | Reported present or known to be present | View Records |
Costa Rica | 2021 | Reported present or known to be present | View Records |
Denmark | 2012 | Reported present or known to be present | View Records |
Ecuador | 2021 | Reported present or known to be present | View Records |
France | 2019 | Reported present or known to be present | View Records |
Hong Kong | 2014 | Reported present or known to be present | View Records |
Hungary | 2016 | Reported present or known to be present | View Records |
India | 2017 | Reported in country for the first time | View Records |
Italy | 2020 | Reported in country for the first time | View Records |
Japan | 2013 | Serological evidence and/or isolation of causative agent, no clinical disease | View Records |
Korea, Republic of | 2022 | Reported present or known to be present | View Records |
Malaysia | 2013 | Suspected but not confirmed | View Records |
Mexico | 2019 | Reported in country for the first time | View Records |
Netherlands | 2018 | Reported present or known to be present | View Records |
Peru | 2016 | Reported in country for the first time | View Records |
Poland | 2021 | Reported present or known to be present | View Records |
Portugal | 2017 | Reported present or known to be present | View Records |
Russian Federation | 2014 | Reported present in specific zones | View Records |
Spain | 2020 | Reported present or known to be present | View Records |
Taipei China | 2023 | Reported present or known to be present | View Records |
Taiwan | 2021 | Reported present or known to be present | View Records |
Thailand | 2017 | Reported present or known to be present | View Records |
U.S.S.R. | 2022 | Reported in country for the first time | View Records |
UK/ Great Britain | 2008 | Enzootic in certain regions | View Records |
United Kingdom | 2019 | Reported present or known to be present | View Records |
United States of America | 2023 | See Publication | View Records |
Uruguay | 2013 | Suspected but not confirmed | View Records |
Venezuela | 2008 | Enzootic in certain regions | View Records |
Species affected
Countries affected
Country | Year | Status | View Records |
---|---|---|---|
Albania | 2012 | Pathogen detected, no clinical disease. | View Records |
Americas | 2007 | Disease exists; distribution and occurrence unknown | View Records |
Argentina | 2006 | First detection in this host | View Records |
Australia | 2020 | Reported present or known to be present | View Records |
Belgium | 2012 | Reported present or known to be present | View Records |
Brazil | 2020 | Reported present or known to be present | View Records |
Canada | 2022 | Reported present or known to be present | View Records |
Chile | 2023 | See Publication | View Records |
China (Peoples Rep. of) | 2020 | Reported present or known to be present | View Records |
Colombia | 2023 | Reported present or known to be present | View Records |
Costa Rica | 2021 | Reported present or known to be present | View Records |
Denmark | 2012 | Reported present or known to be present | View Records |
Ecuador | 2021 | Reported present or known to be present | View Records |
France | 2019 | Reported present or known to be present | View Records |
Hong Kong | 2014 | Reported present or known to be present | View Records |
Hungary | 2016 | Reported present or known to be present | View Records |
India | 2017 | Reported in country for the first time | View Records |
Italy | 2020 | Reported in country for the first time | View Records |
Japan | 2013 | Serological evidence and/or isolation of causative agent, no clinical disease | View Records |
Korea, Republic of | 2022 | Reported present or known to be present | View Records |
Malaysia | 2013 | Suspected but not confirmed | View Records |
Mexico | 2019 | Reported in country for the first time | View Records |
Netherlands | 2018 | Reported present or known to be present | View Records |
Peru | 2016 | Reported in country for the first time | View Records |
Poland | 2021 | Reported present or known to be present | View Records |
Portugal | 2017 | Reported present or known to be present | View Records |
Russian Federation | 2014 | Reported present in specific zones | View Records |
Spain | 2020 | Reported present or known to be present | View Records |
Taipei China | 2023 | Reported present or known to be present | View Records |
Taiwan | 2021 | Reported present or known to be present | View Records |
Thailand | 2017 | Reported present or known to be present | View Records |
U.S.S.R. | 2022 | Reported in country for the first time | View Records |
UK/ Great Britain | 2008 | Enzootic in certain regions | View Records |
United Kingdom | 2019 | Reported present or known to be present | View Records |
United States of America | 2023 | See Publication | View Records |
Uruguay | 2013 | Suspected but not confirmed | View Records |
Venezuela | 2008 | Enzootic in certain regions | View Records |